G6PD Deficiency Test

Glucose-6-Phosphate Dehydrogenase (G6PD) is an enzyme that plays a crucial role in maintaining the health of red blood cells. It helps protect these cells from damage and breakdown by enabling them to function properly.

G6PD deficiency is an inherited condition caused by a mutation on the X chromosome, leading to a shortage of the G6PD enzyme. This deficiency can result in the breakdown of red blood cells, a condition known as haemolysis, which can cause symptoms such as jaundice, anaemia, and dark urine.

G6PD deficiency is tested through a blood test that measures the amount of G6PD enzyme in the red blood cells. This test is particularly important before receiving high-dose vitamin C infusions, as individuals with G6PD deficiency may have adverse reactions to such treatments.

A low G6PD result indicates a deficiency in the G6PD enzyme. This means that the individual has a higher risk of experiencing haemolysis, especially when exposed to certain triggers such as certain medications, foods, or infections. Identifying a low G6PD level is essential for managing health and preventing complications.